Role of lysyl oxidase in myocardial fibrosis: From basic science to clinical aspects

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Chronic, heavy AMPK activation suppresses mTOR, which is the protein synthesis switch
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A small, short clinical study comparing 4 weeks of erdosteine therapy at either 300 mg BID or 300 mg TID in 24 patients with COPD, demonstrated a decrease in 8-isoprostane levels compared to baseline values